Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.35 |
| ▸ | CSF1R | P07333 | 4/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 2/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | BMX | P51813 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.30 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.30 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.30 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.30 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909118 | 0.89 | ABCG2 (0.36) | ABCG2PDE5A | |
| SCHEMBL29909953 | 0.89 | ABCG2 (0.37) | ABCG2PDE5A | |
| SCHEMBL29909024 | 0.86 | ABCG2 (0.37) | EGFRCSF1RABCG2PDE5A | |
| SCHEMBL29909829 | 0.83 | ABCG2 (0.36) | ABCG2PDE5A | |
| SCHEMBL29909687 | 0.82 | ABCG2 (0.37) | ABCG2PDE5A | |
| SCHEMBL29909361 | 0.82 | HSD17B1 (0.39) | ABCG2KDRPDE5A | |
| SCHEMBL29909849 | 0.82 | SCN9A (0.37) | ABCG2KDR | |
| SCHEMBL29909204 | 0.81 | ABCG2 (0.35) | ABCG2PDE5A | |
| SCHEMBL29909758 | 0.81 | ABCG2 (0.37) | ABCG2PDE5A | |
| SCHEMBL29909406 | 0.80 | ABCG2 (0.36) | EGFRABCG2PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |