SCHEMBL29909209

SCHEMBL29909209

Nc1cc2c(cc1F)c(N1CCCc3c(C#CC4CC4)cccc31)nc1nncn12

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
STAT3 P40763 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23576727 1.00 MAPT (0.35) MAPTSTAT3KMT2A
SCHEMBL23601836 0.91 MAPT (0.34) MAPTSTAT3KMT2A
SCHEMBL23577434 0.87 MAPT (0.37) MAPTSTAT3KMT2A
SCHEMBL23577135 0.87 MAPT (0.35) MAPTSTAT3KMT2A
SCHEMBL29909182 0.85 MAPT (0.35) MAPTSTAT3KMT2A
SCHEMBL29909070 0.85 MAPT (0.34) MAPTSTAT3KMT2A
SCHEMBL23576708 0.85 MAPT (0.35) MAPTSTAT3KMT2A
SCHEMBL29909595 0.83 MAPT (0.39) MAPTSTAT3KMT2A
SCHEMBL23577278 0.83 MAPT (0.39) MAPTSTAT3KMT2A
SCHEMBL23578144 0.80 MAPT (0.36) MAPTSTAT3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324767-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2024-07-12 CN disclosed
CN-115362003-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2022-11-18 CN disclosed
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed