Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577278 | 1.00 | MAPT (0.39) | MAPTSTAT3KMT2APOLBSMN1; SMN2 | |
| SCHEMBL23577434 | 0.87 | MAPT (0.37) | MAPTSTAT3KMT2APOLBSMN1; SMN2 | |
| SCHEMBL23578144 | 0.86 | MAPT (0.36) | MAPTSTAT3KMT2APOLBSMN1; SMN2 | |
| SCHEMBL23576783 | 0.86 | MAPT (0.38) | MAPTSTAT3KMT2APOLBSMN1; SMN2 | |
| SCHEMBL29909809 | 0.86 | MAPT (0.38) | MAPTSTAT3KMT2APOLBSMN1; SMN2 | |
| SCHEMBL29909264 | 0.85 | KMT2A (0.52) | MAPTSTAT3KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL23577076 | 0.85 | KMT2A (0.52) | MAPTSTAT3KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL23601228 | 0.85 | MAPT (0.35) | MAPTSTAT3KMT2APOLBSMN1; SMN2 | |
| SCHEMBL23577135 | 0.83 | MAPT (0.35) | MAPTSTAT3KMT2APOLBSMN1; SMN2 | |
| SCHEMBL29909209 | 0.83 | MAPT (0.35) | MAPTSTAT3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |