Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577132 | 1.00 | ABCG2 (0.43) | ABCG2HCRTR1EGFRF2F10 | |
| SCHEMBL29909160 | 0.89 | ABCG2 (0.38) | ABCG2EGFRMAPTADORA2AADORA2B | |
| SCHEMBL23577162 | 0.89 | ABCG2 (0.38) | ABCG2EGFRMAPTADORA2AADORA2B | |
| SCHEMBL23600979 | 0.88 | EGFR (0.44) | EGFRMAPT | |
| SCHEMBL23577019 | 0.87 | ABCG2 (0.43) | ABCG2HCRTR1EGFRMAPT | |
| SCHEMBL29909802 | 0.87 | ABCG2 (0.43) | ABCG2HCRTR1EGFRMAPT | |
| SCHEMBL31229721 | 0.86 | ABCG2 (0.52) | ABCG2HCRTR1 | |
| SCHEMBL23577419 | 0.86 | ABCG2 (0.52) | ABCG2HCRTR1 | |
| SCHEMBL23576699 | 0.86 | ABCG2 (0.42) | ABCG2HCRTR1F2F10MAPT | |
| SCHEMBL23577063 | 0.86 | ABCG2 (0.38) | ABCG2EGFRADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-B1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES INC (JP) | 2024-09-18 | — | — | EP | disclosed |
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |