Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577162 | 1.00 | ABCG2 (0.38) | ABCG2DHODHSMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL23577063 | 0.92 | ABCG2 (0.38) | ABCG2DHODHADORA2AADORA1EGFR | |
| SCHEMBL29909869 | 0.92 | ABCG2 (0.38) | ABCG2DHODHADORA2AADORA1EGFR | |
| SCHEMBL29909005 | 0.91 | MAPT (0.33) | ABCG2DHODHSMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL23576893 | 0.91 | MAPT (0.33) | ABCG2DHODHSMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL23577132 | 0.89 | ABCG2 (0.43) | ABCG2ADORA2AMAPTADORA2BEGFR | |
| SCHEMBL29909229 | 0.89 | ABCG2 (0.43) | ABCG2ADORA2AMAPTADORA2BEGFR | |
| SCHEMBL23576965 | 0.89 | TP53 (0.37) | MAPTTP53EGFR | |
| SCHEMBL29909323 | 0.89 | TP53 (0.37) | MAPTTP53EGFR | |
| SCHEMBL23576621 | 0.88 | ABCG2 (0.45) | ABCG2DHODHSMN1; SMN2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |