Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577652 | 1.00 | ABCG2 (0.46) | ABCG2EGFRKDRPDGFRB | |
| SCHEMBL23576665 | 0.91 | ABCG2 (0.50) | ABCG2 | |
| SCHEMBL29909290 | 0.91 | ABCG2 (0.50) | ABCG2 | |
| SCHEMBL29909037 | 0.90 | ABCG2 (0.39) | ABCG2 | |
| SCHEMBL23577303 | 0.90 | ABCG2 (0.39) | ABCG2 | |
| SCHEMBL23601350 | 0.85 | ABCG2 (0.50) | ABCG2EGFRKDRPDGFRB | |
| SCHEMBL29909084 | 0.85 | ABCG2 (0.50) | ABCG2EGFRKDRPDGFRB | |
| SCHEMBL23576685 | 0.84 | EGFR (0.43) | ABCG2EGFRKDRPDGFRB | |
| SCHEMBL29909891 | 0.84 | EGFR (0.43) | ABCG2EGFRKDRPDGFRB | |
| SCHEMBL23576724 | 0.83 | ABCG2 (0.49) | ABCG2EGFRKDRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |