SCHEMBL29909290

SCHEMBL29909290

CN(c1cccc(F)c1)c1nc(NN)nc2cc(F)c(F)cc12

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.50
KDM1A O60341 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23576665 1.00 ABCG2 (0.50) ABCG2KDM1A
SCHEMBL23577652 0.91 ABCG2 (0.46) ABCG2
SCHEMBL29909237 0.91 ABCG2 (0.46) ABCG2
SCHEMBL23577974 0.89 KDM1A (0.43) ABCG2KDM1A
SCHEMBL23576685 0.88 EGFR (0.43) ABCG2KDM1A
SCHEMBL29909891 0.88 EGFR (0.43) ABCG2KDM1A
SCHEMBL23601350 0.85 ABCG2 (0.50) ABCG2
SCHEMBL29909084 0.85 ABCG2 (0.50) ABCG2
SCHEMBL23576718 0.81 ABCG2 (0.47) ABCG2
SCHEMBL23577016 0.81 ABCG2 (0.53) ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324767-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2024-07-12 CN disclosed
CN-115362003-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2022-11-18 CN disclosed
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed