Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.34 |
| ▸ | TUBB | P07437 | 4/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577076 | 1.00 | KMT2A (0.52) | KMT2ASTAT3MAPTROCK1ALDH1A1 | |
| SCHEMBL23577062 | 0.97 | KMT2A (0.48) | KMT2ASTAT3MAPTROCK1ALDH1A1 | |
| SCHEMBL29909088 | 0.93 | KMT2A (0.54) | KMT2ASTAT3MAPTROCK1ALDH1A1 | |
| SCHEMBL23576636 | 0.93 | KMT2A (0.54) | KMT2ASTAT3MAPTROCK1ALDH1A1 | |
| SCHEMBL23577180 | 0.90 | KMT2A (0.46) | KMT2ASTAT3MAPTROCK1ALDH1A1 | |
| SCHEMBL29909952 | 0.89 | STAT3 (0.39) | KMT2ASTAT3MAPTROCK1 | |
| SCHEMBL23576993 | 0.89 | STAT3 (0.39) | KMT2ASTAT3MAPTROCK1 | |
| SCHEMBL23601794 | 0.89 | KMT2A (0.51) | KMT2ASTAT3MAPTROCK1ALDH1A1 | |
| SCHEMBL23576884 | 0.87 | STAT3 (0.38) | KMT2ASTAT3MAPTEGFR | |
| SCHEMBL29909213 | 0.87 | STAT3 (0.38) | KMT2ASTAT3MAPTEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |