Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | CTPS1 | P17812 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576714 | 1.00 | NPC1 (0.38) | NPC1RAB9ATP53FNTAFNTB | |
| SCHEMBL29909468 | 0.91 | TP53 (0.47) | NPC1RAB9ATP53FNTAFNTB | |
| SCHEMBL23576656 | 0.91 | TP53 (0.39) | TP53FNTAFNTBCNR1PLAU | |
| SCHEMBL23576968 | 0.91 | TP53 (0.47) | NPC1RAB9ATP53FNTAFNTB | |
| SCHEMBL23601388 | 0.90 | ATM (0.40) | TP53FNTAFNTBCNR1PLAU | |
| SCHEMBL29909202 | 0.90 | ATM (0.40) | TP53FNTAFNTBCNR1PLAU | |
| SCHEMBL29909768 | 0.86 | FNTA (0.40) | TP53FNTAFNTBF10KDM4E | |
| SCHEMBL23601235 | 0.86 | FNTA (0.40) | TP53FNTAFNTBF10KDM4E | |
| SCHEMBL23601858 | 0.85 | FNTA (0.39) | TP53FNTAFNTBCNR1F10 | |
| SCHEMBL31229755 | 0.85 | FNTA (0.39) | TP53FNTAFNTBCNR1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |