Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576968 | 1.00 | TP53 (0.47) | TP53TDP1KDM4EMEN1ALDH1A1 | |
| SCHEMBL23576656 | 0.93 | TP53 (0.39) | TP53PLAUF10CNR1FNTA | |
| SCHEMBL29909287 | 0.91 | NPC1 (0.38) | TP53KDM4ENPC1RAB9APLAU | |
| SCHEMBL23576714 | 0.91 | NPC1 (0.38) | TP53KDM4ENPC1RAB9APLAU | |
| SCHEMBL29909552 | 0.90 | AOC3 (0.38) | TP53KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL29909015 | 0.90 | IDO1 (0.37) | TP53KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL23577153 | 0.90 | AOC3 (0.38) | TP53KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL23577181 | 0.90 | IDO1 (0.37) | TP53KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL23601408 | 0.89 | KMT2A (0.39) | TP53KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL29909110 | 0.89 | KMT2A (0.39) | TP53KDM4EMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-B1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES INC (JP) | 2024-09-18 | — | — | EP | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |