SCHEMBL29909309

SCHEMBL29909309

CC1(C#Cc2cccc(N(CC3CC3)c3nc4nncn4c4cc(Cl)ccc34)c2)CC1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FGFR3 P22607 1/20 0.31
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23577634 1.00 FGFR3 (0.31) FGFR3TP53MAPT
SCHEMBL23577396 0.87 TP53 (0.30) TP53MAPT
SCHEMBL29909555 0.81 MAPT (0.32) TP53MAPT
SCHEMBL23577594 0.81 MAPT (0.32) TP53MAPT
SCHEMBL29909494 0.81 FGFR3 (0.32) FGFR3
SCHEMBL23601245 0.80
SCHEMBL23576759 0.78
SCHEMBL23578417 0.77 PTGES (0.37)
SCHEMBL23600999 0.77 PTGES (0.39)
SCHEMBL29909373 0.77 PTGES (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4445902-A2 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2024-10-16 EP disclosed
CN-118324767-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2024-07-12 CN disclosed
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed