SCHEMBL29909384

SCHEMBL29909384

CN(c1cccc(C#C[C@@](C)(O)CF)c1)c1nc2nncn2c2cc(Cl)ccc12

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
MAT2A P31153 3/20 0.31
PRMT5 O14744 1/20 0.31
CYP1A2 P05177 1/20 0.31
MAP3K14 Q99558 2/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24721442 1.00 FNTA (0.31) FNTAFNTBMAT2APRMT5CYP1A2
SCHEMBL23576786 1.00 FNTA (0.31) FNTAFNTBMAT2APRMT5CYP1A2
SCHEMBL29909594 1.00 FNTA (0.31) FNTAFNTBMAT2APRMT5CYP1A2
SCHEMBL23576784 1.00 FNTA (0.31) FNTAFNTBMAT2APRMT5CYP1A2
SCHEMBL23601039 0.91 PTGES (0.36) FNTAFNTBMAT2APRMT5CYP1A2
SCHEMBL23601829 0.90 MAP3K14 (0.32) FNTAFNTBMAT2APRMT5CYP1A2
SCHEMBL29909004 0.89 FNTA (0.32) FNTAFNTBMAP3K14
SCHEMBL23601290 0.89 FNTA (0.32) FNTAFNTBMAP3K14
SCHEMBL23601040 0.89 FNTA (0.34) FNTAFNTBMAT2APRMT5CYP1A2
SCHEMBL23576764 0.88 FNTA (0.31) FNTAFNTBMAP3K14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed