Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.32 |
| ▸ | PDE5A | O76074 | 2/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909227 | 0.84 | ABCG2 (0.34) | ABCG2PDE5A | |
| SCHEMBL29909333 | 0.82 | ABCG2 (0.33) | ABCG2PDE5A | |
| SCHEMBL29909542 | 0.81 | ABCG2 (0.34) | ABCG2PDE5A | |
| SCHEMBL29909524 | 0.81 | KDM4E (0.38) | KDM4ENPC1ALDH1A1TP53MAPT | |
| SCHEMBL29909600 | 0.81 | ABCG2 (0.32) | ABCG2PDE5A | |
| SCHEMBL29909714 | 0.81 | MAP3K5 (0.33) | ABCG2PDE5A | |
| SCHEMBL29909736 | 0.80 | GRM5 (0.33) | ABCG2PDE5A | |
| SCHEMBL23601015 | 0.79 | EGFR (0.37) | KDM4ENPC1ALDH1A1TP53MAPT | |
| SCHEMBL31169430 | 0.79 | EGFR (0.37) | KDM4ENPC1ALDH1A1TP53MAPT | |
| SCHEMBL29909406 | 0.77 | ABCG2 (0.36) | MAPTEGFRABCG2PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |