Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 7/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.36 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.36 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | CACNA1E | Q15878 | 1/20 | 0.36 |
| ▸ | CACNA2D4 | Q7Z3S7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601641 | 1.00 | CHEK2 (0.37) | CHEK2F10CACNB4CACNA1ACACNA1G | |
| SCHEMBL23577171 | 0.91 | CHEK2 (0.41) | CHEK2CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL29909389 | 0.91 | CHEK2 (0.41) | CHEK2CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL23577741 | 0.90 | HRH4 (0.36) | CHEK2 | |
| SCHEMBL23577204 | 0.87 | KHK (0.40) | — | |
| SCHEMBL29909411 | 0.87 | KHK (0.40) | — | |
| SCHEMBL23577205 | 0.87 | KHK (0.40) | — | |
| SCHEMBL23600788 | 0.84 | CHEK2 (0.37) | CHEK2F10CACNB4CACNA1ACACNA1G | |
| SCHEMBL23600785 | 0.82 | TP53 (0.37) | KDR | |
| SCHEMBL29909398 | 0.82 | TP53 (0.37) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |