Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 5/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23600785 | 1.00 | TP53 (0.37) | TP53EGFRPDGFRBKDRAURKA | |
| SCHEMBL29909768 | 0.92 | FNTA (0.40) | TP53ALDH1A1FNTAFNTBMAPT | |
| SCHEMBL23601235 | 0.92 | FNTA (0.40) | TP53ALDH1A1FNTAFNTBMAPT | |
| SCHEMBL30920925 | 0.90 | TP53 (0.39) | TP53FNTAFNTBCSF1RMAPT | |
| SCHEMBL24721227 | 0.90 | TP53 (0.41) | TP53EGFRPDGFRBKDRALDH1A1 | |
| SCHEMBL23577190 | 0.89 | MAT2A (0.37) | TP53EGFRALDH1A1FNTAFNTB | |
| SCHEMBL29909135 | 0.89 | MAT2A (0.37) | TP53EGFRALDH1A1FNTAFNTB | |
| SCHEMBL23576643 | 0.89 | NPM1 (0.39) | TP53EGFRPDGFRBKDRALDH1A1 | |
| SCHEMBL23576965 | 0.89 | TP53 (0.37) | TP53EGFRPDGFRBKDRALDH1A1 | |
| SCHEMBL29909323 | 0.89 | TP53 (0.37) | TP53EGFRPDGFRBKDRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |