Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9600901 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2HTTKDM4EMAPK1MAPT | |
| SCHEMBL29909232 | 0.79 | HRH4 (0.43) | SMN1; SMN2KDM4EMAPTKMT2ATNKS2 | |
| SCHEMBL23577370 | 0.79 | HRH4 (0.43) | SMN1; SMN2KDM4EMAPTKMT2ATNKS2 | |
| SCHEMBL11708978 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EMAPK1MAPTALDH1A1 | |
| SCHEMBL29909498 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2KDM4EMAPK1MAPTALDH1A1 | |
| SCHEMBL29909609 | 0.77 | KDM4E (0.37) | SMN1; SMN2HTTKDM4EMAPTALDH1A1 | |
| SCHEMBL23576802 | 0.77 | KDM4E (0.37) | SMN1; SMN2HTTKDM4EMAPTALDH1A1 | |
| SCHEMBL11708286 | 0.76 | POLB (0.46) | SMN1; SMN2HTTKDM4EMAPK1MAPT | |
| SCHEMBL24131213 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2KDM4EMAPK1MAPTKMT2A | |
| SCHEMBL30979133 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2HTTKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |