Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577370 | 1.00 | HRH4 (0.43) | HRH4PARP15TNKS2PARP2SMN1; SMN2 | |
| SCHEMBL29909609 | 0.84 | KDM4E (0.37) | HRH4PARP15TNKS2PARP2SMN1; SMN2 | |
| SCHEMBL23576802 | 0.84 | KDM4E (0.37) | HRH4PARP15TNKS2PARP2SMN1; SMN2 | |
| SCHEMBL23601428 | 0.80 | MAT2A (0.48) | HRH4SMN1; SMN2MAPT | |
| SCHEMBL9600901 | 0.79 | SMN1; SMN2 (0.46) | TNKS2PARP2SMN1; SMN2KDM4ETP53 | |
| SCHEMBL29909443 | 0.79 | SMN1; SMN2 (0.46) | TNKS2PARP2SMN1; SMN2KDM4ETP53 | |
| SCHEMBL23577365 | 0.78 | HRH4 (0.43) | HRH4SMN1; SMN2HRH3KDM4EMAPT | |
| SCHEMBL30013724 | 0.78 | HRH4 (0.43) | HRH4SMN1; SMN2HRH3KDM4EMAPT | |
| SCHEMBL23601930 | 0.76 | MAT2A (0.41) | HRH4PARP15TNKS2PARP2SMN1; SMN2 | |
| SCHEMBL30961036 | 0.74 | CSF1R (0.44) | HRH4TP53MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |