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SCHEMBL29909493

SCHEMBL29909493

CN(c1cccc(-c2cnc(C(C)(C)C)cn2)c1)c1nc2nncn2c2cc(Cl)ccc12

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 1/20 0.36
▸ FNTB P49356 1/20 0.36
▸ TP53 P04637 2/20 0.32
▸ MAPT P10636 2/20 0.32
▸ POLB P06746 1/20 0.31
▸ CSNK2A2 P19784 1/20 0.30
▸ CSNK2B P67870 1/20 0.30
▸ MAT2A P31153 2/20 0.30
▸ CCR9 P51686 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23576662 1.00 FNTA (0.36) FNTAFNTBTP53MAPTPOLB
SCHEMBL23601617 0.93 FNTA (0.36) FNTAFNTBTP53MAPTPOLB
SCHEMBL29909025 0.89 FNTA (0.37) FNTAFNTBTP53MAPTCSNK2A2
SCHEMBL23577131 0.89 FNTA (0.37) FNTAFNTBTP53MAPTCSNK2A2
SCHEMBL23601645 0.89 FNTA (0.36) FNTAFNTBTP53MAPTPOLB
SCHEMBL23600551 0.88 FNTA (0.40) FNTAFNTBTP53MAPTPOLB
SCHEMBL29909786 0.88 FNTA (0.36) FNTAFNTBTP53MAPTPOLB
SCHEMBL23576904 0.88 FNTA (0.36) FNTAFNTBTP53MAPTPOLB
SCHEMBL23576916 0.87 FNTA (0.36) FNTAFNTBTP53MAPTPOLB
SCHEMBL23601440 0.85 FNTA (0.34) FNTAFNTBTP53MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 — — EP disclosed