Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 3/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577329 | 1.00 | EGFR (0.44) | EGFRPDGFRBKDRCSNK2A2CSNK2B | |
| SCHEMBL23578029 | 0.87 | EGFR (0.59) | EGFRPDGFRBKDRABCG2PDE5A | |
| SCHEMBL30013192 | 0.87 | EGFR (0.59) | EGFRPDGFRBKDRABCG2PDE5A | |
| SCHEMBL29909851 | 0.86 | EGFR (0.47) | EGFRPDGFRBKDRCSNK2A2CSNK2B | |
| SCHEMBL23577167 | 0.86 | EGFR (0.47) | EGFRPDGFRBKDRCSNK2A2CSNK2B | |
| SCHEMBL23577274 | 0.85 | EGFR (0.59) | EGFRPDGFRBKDRCSNK2A2CSNK2B | |
| SCHEMBL30014151 | 0.85 | EGFR (0.59) | EGFRPDGFRBKDRCSNK2A2CSNK2B | |
| SCHEMBL23576849 | 0.84 | EGFR (0.41) | EGFRPDGFRBKDRCSNK2A2CSNK2B | |
| SCHEMBL29909472 | 0.84 | EGFR (0.41) | EGFRPDGFRBKDRCSNK2A2CSNK2B | |
| SCHEMBL23576645 | 0.84 | ESR1 (0.34) | EGFRPDGFRBKDRCHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4359413-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117396478-A | Diacylglycerol kinase modulating compounds | 吉利德科学公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2022271650-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |