Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576849 | 1.00 | EGFR (0.41) | EGFRKDRPDGFRBGAAMAPT | |
| SCHEMBL23577187 | 0.87 | GAA (0.50) | GAAMAPTCSF1RCHKA | |
| SCHEMBL30961048 | 0.87 | GAA (0.50) | GAAMAPTCSF1RCHKA | |
| SCHEMBL29909619 | 0.86 | GAA (0.40) | EGFRKDRGAAMAPTKMT2A | |
| SCHEMBL23577455 | 0.86 | GAA (0.40) | EGFRKDRGAAMAPTKMT2A | |
| SCHEMBL23577329 | 0.84 | EGFR (0.44) | EGFRKDRPDGFRBCSNK2A2CSNK2B | |
| SCHEMBL29909602 | 0.84 | EGFR (0.44) | EGFRKDRPDGFRBCSNK2A2CSNK2B | |
| SCHEMBL24807698 | 0.84 | GAA (0.36) | GAAMAPTKMT2ACSF1RCHKA | |
| SCHEMBL23601713 | 0.83 | CHKA (0.39) | KDRGAAMAPTKMT2ACSNK2A2 | |
| SCHEMBL23576685 | 0.83 | EGFR (0.43) | EGFRKDRPDGFRBGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |