Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 2/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.31 |
| ▸ | RXRA | P19793 | 2/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909415 | 0.89 | RORC (0.37) | ABCG2DHODHPTGS1PTGS2PDE5A | |
| SCHEMBL29909330 | 0.88 | CYP1A2 (0.38) | ABCG2DHODH | |
| SCHEMBL29909021 | 0.87 | ABCG2 (0.34) | ABCG2DHODHPDE5ANR1H2NR1H3 | |
| SCHEMBL29909024 | 0.86 | ABCG2 (0.37) | ABCG2DHODHPDE5AKIF11 | |
| SCHEMBL29909829 | 0.85 | ABCG2 (0.36) | ABCG2DHODHPDE5A | |
| SCHEMBL30961045 | 0.85 | KCNH2 (0.34) | ABCG2DHODHPDE5A | |
| SCHEMBL29909758 | 0.85 | ABCG2 (0.37) | ABCG2DHODHPDE5A | |
| SCHEMBL29909687 | 0.85 | ABCG2 (0.37) | ABCG2DHODHPDE5A | |
| SCHEMBL29909683 | 0.84 | RORC (0.34) | ABCG2DHODHPDE5A | |
| SCHEMBL29909204 | 0.84 | ABCG2 (0.35) | ABCG2DHODHPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |