Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.36 |
| ▸ | PDE5A | O76074 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576624 | 1.00 | KDR (0.38) | KDRABCG2PDE5AHTR1DSMN1; SMN2 | |
| SCHEMBL23578033 | 0.88 | PDE5A (0.44) | ABCG2PDE5ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL29909324 | 0.87 | HTR1D (0.41) | KDRPDE5AHTR1DPDGFRBPDGFRA | |
| SCHEMBL23576923 | 0.87 | HTR1D (0.41) | KDRPDE5AHTR1DPDGFRBPDGFRA | |
| SCHEMBL23576620 | 0.86 | ABCG2 (0.38) | ABCG2PDE5ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL29909534 | 0.86 | ABCG2 (0.38) | ABCG2PDE5ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL30979054 | 0.85 | SMN1; SMN2 (0.37) | KDRPDE5ASMN1; SMN2TSHR | |
| SCHEMBL23577734 | 0.85 | SMN1; SMN2 (0.37) | KDRPDE5ASMN1; SMN2TSHR | |
| SCHEMBL23601567 | 0.84 | ABCG2 (0.51) | ABCG2PDE5ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL23578009 | 0.84 | ALDH1A1 (0.39) | ABCG2PDE5ASMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |