SCHEMBL29909613

SCHEMBL29909613

Cc1nnc2nc(N3CCOc4c(C#CC(C)(C)C(F)(F)F)cccc43)c3cc(F)ccc3n12

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTAFR P25105 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24721319 1.00 PTAFR (0.33) PTAFR
SCHEMBL24816014 0.88 DHODH (0.31) PTAFR
SCHEMBL23578193 0.87 PTAFR (0.30) PTAFR
SCHEMBL23601843 0.86 MAPT (0.32)
SCHEMBL29909157 0.86 MAPT (0.32)
SCHEMBL23577406 0.85 PTAFR (0.33) PTAFR
SCHEMBL24815998 0.84 PTAFR (0.31) PTAFR
SCHEMBL23601548 0.84 PIK3CD (0.35) PTAFR
SCHEMBL23576989 0.83
SCHEMBL23576677 0.82 PIK3CA (0.32) PTAFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed