Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PTAFR | P25105 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601077 | 0.95 | DHODH (0.33) | PIK3CDDHODHPTAFRMAPT | |
| SCHEMBL23576677 | 0.91 | PIK3CA (0.32) | PTAFRPIK3CBPIK3CGPIK3CA | |
| SCHEMBL29909207 | 0.91 | PIK3CA (0.32) | PTAFRPIK3CBPIK3CGPIK3CA | |
| SCHEMBL23601076 | 0.85 | MAPT (0.39) | PIK3CDDHODHCYP17A1CYP1A2PIK3CB | |
| SCHEMBL29909613 | 0.84 | PTAFR (0.33) | PTAFR | |
| SCHEMBL24721319 | 0.84 | PTAFR (0.33) | PTAFR | |
| SCHEMBL24721318 | 0.84 | — | — | |
| SCHEMBL23601078 | 0.82 | DHODH (0.39) | DHODHPTAFRMAPT | |
| SCHEMBL23578193 | 0.82 | PTAFR (0.30) | PTAFR | |
| SCHEMBL23601546 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |