Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.35 |
| ▸ | TUBB | P07437 | 4/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601737 | 1.00 | KMT2A (0.53) | KMT2ASTAT3ROCK1NUDT1MEN1 | |
| SCHEMBL29909921 | 0.88 | STAT3 (0.54) | KMT2ASTAT3ROCK1NUDT1TUBB4A | |
| SCHEMBL23576676 | 0.88 | STAT3 (0.54) | KMT2ASTAT3ROCK1NUDT1TUBB4A | |
| SCHEMBL30979080 | 0.87 | KMT2A (0.63) | KMT2ASTAT3ROCK1NUDT1MEN1 | |
| SCHEMBL23601720 | 0.87 | KMT2A (0.63) | KMT2ASTAT3ROCK1NUDT1MEN1 | |
| SCHEMBL23576857 | 0.85 | KMT2A (0.51) | KMT2ASTAT3ROCK1NUDT1MEN1 | |
| SCHEMBL29909597 | 0.85 | KMT2A (0.51) | KMT2ASTAT3ROCK1NUDT1MEN1 | |
| SCHEMBL23577362 | 0.85 | KMT2A (0.51) | KMT2ASTAT3ROCK1NUDT1MEN1 | |
| SCHEMBL23601270 | 0.85 | STAT3 (0.51) | KMT2ASTAT3ROCK1NUDT1TUBB4A | |
| SCHEMBL29909334 | 0.85 | KMT2A (0.51) | KMT2ASTAT3ROCK1NUDT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |