Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | STAT3 | P40763 | 1/20 | 0.63 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.39 |
| ▸ | TUBB | P07437 | 5/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601720 | 1.00 | KMT2A (0.63) | KMT2ASTAT3ROCK1TUBB4ATUBB | |
| SCHEMBL23578040 | 0.96 | STAT3 (0.58) | KMT2ASTAT3ROCK1TUBB4ATUBB | |
| SCHEMBL29909558 | 0.96 | STAT3 (0.58) | KMT2ASTAT3ROCK1TUBB4ATUBB | |
| SCHEMBL29909471 | 0.95 | STAT3 (0.57) | KMT2ASTAT3ROCK1TUBB4ATUBB | |
| SCHEMBL23576798 | 0.95 | STAT3 (0.57) | KMT2ASTAT3ROCK1TUBB4ATUBB | |
| SCHEMBL23576676 | 0.88 | STAT3 (0.54) | KMT2ASTAT3ROCK1TUBB4ATUBB | |
| SCHEMBL29909921 | 0.88 | STAT3 (0.54) | KMT2ASTAT3ROCK1TUBB4ATUBB | |
| SCHEMBL23601737 | 0.87 | KMT2A (0.53) | KMT2ASTAT3ROCK1TUBB4ATUBB | |
| SCHEMBL29909671 | 0.87 | KMT2A (0.53) | KMT2ASTAT3ROCK1TUBB4ATUBB | |
| SCHEMBL30013879 | 0.87 | STAT3 (0.53) | KMT2ASTAT3ROCK1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |