Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.35 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576897 | 1.00 | CHEK2 (0.41) | CHEK2CSNK2A1FGFR1CSNK2A2CSNK2B | |
| SCHEMBL29909942 | 0.91 | CSNK2A1 (0.47) | CSNK2A1FGFR1CSNK2A2CSNK2BPDE5A | |
| SCHEMBL23577221 | 0.91 | CSNK2A1 (0.47) | CSNK2A1FGFR1CSNK2A2CSNK2BPDE5A | |
| SCHEMBL29909496 | 0.87 | FGFR1 (0.42) | CSNK2A1FGFR1CSNK2A2CSNK2BMAPT | |
| SCHEMBL23576749 | 0.87 | FGFR1 (0.42) | CSNK2A1FGFR1CSNK2A2CSNK2BMAPT | |
| SCHEMBL23577198 | 0.87 | CRY1 (0.44) | CHEK2PDE5ACRY1CRY2MAOA | |
| SCHEMBL23578069 | 0.83 | EGFR (0.47) | CSNK2A1CSNK2A2CSNK2BPDE5AMAPT | |
| SCHEMBL29909077 | 0.83 | EGFR (0.47) | CSNK2A1CSNK2A2CSNK2BPDE5AMAPT | |
| SCHEMBL30961004 | 0.82 | PDE5A (0.44) | PDE5ASMN1; SMN2 | |
| SCHEMBL23577222 | 0.82 | PDE5A (0.44) | PDE5ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |