Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29909280 | 0.90 | FNTA (0.33) | TP53MAPTFNTAFNTBHTT | |
| SCHEMBL23577495 | 0.89 | TP53 (0.35) | TP53MAPTFNTAFNTBPOLB | |
| SCHEMBL23601645 | 0.85 | FNTA (0.36) | TP53MAPTFNTAFNTBPOLB | |
| SCHEMBL29909087 | 0.84 | TP53 (0.35) | TP53MAPTFNTAFNTBPOLB | |
| SCHEMBL23577160 | 0.83 | JAK2 (0.35) | TP53MAPT | |
| SCHEMBL23601617 | 0.83 | FNTA (0.36) | TP53MAPTFNTAFNTBPOLB | |
| SCHEMBL29909493 | 0.83 | FNTA (0.36) | TP53MAPTFNTAFNTBPOLB | |
| SCHEMBL23576662 | 0.83 | FNTA (0.36) | TP53MAPTFNTAFNTBPOLB | |
| SCHEMBL23601440 | 0.82 | FNTA (0.34) | TP53MAPTFNTAFNTBPOLB | |
| SCHEMBL31169400 | 0.82 | FNTA (0.34) | TP53MAPTFNTAFNTBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |