Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576748 | 1.00 | CYP1A2 (0.44) | CYP1A2CLK4CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL23601282 | 0.94 | DYRK1A (0.44) | CYP1A2CLK4CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL29909776 | 0.94 | DYRK1A (0.44) | CYP1A2CLK4CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL23577808 | 0.93 | EGFR (0.40) | CYP1A2CLK4CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL29909632 | 0.93 | EGFR (0.40) | CYP1A2CLK4CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL23578033 | 0.89 | PDE5A (0.44) | MAPK1HSD17B10TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL29909130 | 0.86 | HTR7 (0.40) | CYP1A2CYP3A4CYP2D6CYP2C19USP2 | |
| SCHEMBL23576941 | 0.86 | HTR7 (0.40) | CYP1A2CYP3A4CYP2D6CYP2C19USP2 | |
| SCHEMBL23601567 | 0.85 | ABCG2 (0.51) | MAPK1TSHRSMN1; SMN2ALDH1A1ABCG2 | |
| SCHEMBL23576620 | 0.85 | ABCG2 (0.38) | MAPK1HSD17B10TSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |