SCHEMBL29909845

SCHEMBL29909845

CN(c1cccc(-c2ccc(C(C)(F)F)nc2)c1)c1nc2nncn2c2cc(Cl)ccc12

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.36
FNTB P49356 1/20 0.36
PSD A5PKW4 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
DHODH Q02127 1/20 0.30
CSNK2A2 P19784 1/20 0.30
CSNK2B P67870 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23601379 1.00 FNTA (0.36) FNTAFNTBPSDABCG2DHODH
SCHEMBL23601434 0.94 FNTA (0.36) FNTAFNTBPSDABCG2
SCHEMBL31169421 0.94 FNTA (0.36) FNTAFNTBPSDABCG2
SCHEMBL29909025 0.93 FNTA (0.37) FNTAFNTBABCG2CSNK2A2CSNK2B
SCHEMBL23577131 0.93 FNTA (0.37) FNTAFNTBABCG2CSNK2A2CSNK2B
SCHEMBL23577097 0.92 FNTA (0.36) FNTAFNTBDHODHCSNK2A2CSNK2B
SCHEMBL29909557 0.89 FNTA (0.37) FNTAFNTBABCG2DHODHCSNK2A2
SCHEMBL23576895 0.89 FNTA (0.37) FNTAFNTBABCG2DHODHCSNK2A2
SCHEMBL23577354 0.88 FNTA (0.35) FNTAFNTBPSDABCG2TP53
SCHEMBL23577102 0.88 FNTA (0.41) FNTAFNTBABCG2DHODHCSNK2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324767-A Diacylglycerol kinase modulating compounds 卡尔那生物科学株式会社 2024-07-12 CN disclosed
EP-4081305-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2022-11-02 EP disclosed