Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577421 | 1.00 | CSNK2A1 (0.40) | CSNK2A1FGFR1GABRG2GABRB3GABRA5 | |
| SCHEMBL23576749 | 0.92 | FGFR1 (0.42) | CSNK2A1FGFR1GABRG2GABRB3GABRA5 | |
| SCHEMBL29909496 | 0.92 | FGFR1 (0.42) | CSNK2A1FGFR1GABRG2GABRB3GABRA5 | |
| SCHEMBL23578062 | 0.89 | CSNK2A1 (0.50) | CSNK2A1FGFR1CSNK2A2CSNK2BKDM4E | |
| SCHEMBL23577364 | 0.87 | GABRG2 (0.41) | GABRG2GABRB3GABRA5GABRA3KMT2A | |
| SCHEMBL29909321 | 0.87 | GABRG2 (0.41) | GABRG2GABRB3GABRA5GABRA3KMT2A | |
| SCHEMBL23576795 | 0.84 | CSNK2A1 (0.38) | CSNK2A1CSNK2A2CSNK2BSMN1; SMN2MAPT | |
| SCHEMBL29909235 | 0.84 | CSNK2A1 (0.38) | CSNK2A1CSNK2A2CSNK2BSMN1; SMN2MAPT | |
| SCHEMBL23578083 | 0.83 | CSNK2A1 (0.37) | CSNK2A1CSNK2A2CSNK2BSMN1; SMN2MAPT | |
| SCHEMBL23578086 | 0.83 | CSNK2A1 (0.37) | CSNK2A1CSNK2A2CSNK2BSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081305-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2022-11-02 | — | — | EP | disclosed |