Cliprofen

Cliprofen

SCHEMBL29910028

CC(C(=O)O)c1ccc(C(=O)c2cccs2)c(Cl)c1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 4/20 0.63
HPGD P15428 4/20 0.63
ALDH1A1 P00352 4/20 0.63
CYP2C9 P11712 3/20 0.63
LMNA P02545 3/20 0.63
PTGS2 P35354 3/20 0.63
KDM4E B2RXH2 2/20 0.63
RXFP1 Q9HBX9 1/20 0.63
CHRM1 P11229 1/20 0.47
ALOX15 P16050 2/20 0.46
SMN1; SMN2 Q16637 4/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
MAPT P10636 3/20 0.43
HSD17B10 Q99714 2/20 0.43
PSMD14 O00487 1/20 0.43
MMP2 P08253 1/20 0.43
HPGDS O60760 1/20 0.42
AKR1C3 P42330 3/20 0.41
AKR1C2 P52895 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cliprofen SCHEMBL11702737 1.00 PTGS1 (0.63) PTGS1HPGDALDH1A1CYP2C9LMNA
Cliprofen SCHEMBL42298 1.00 PTGS1 (0.63) PTGS1HPGDALDH1A1CYP2C9LMNA
SCHEMBL11706148 0.86 HPGD (0.46) PTGS1HPGDALDH1A1CYP2C9LMNA
SCHEMBL11703127 0.85 PTGS1 (0.68) PTGS1HPGDALDH1A1CYP2C9LMNA
SCHEMBL11703120 0.85 PTGS1 (0.68) PTGS1HPGDALDH1A1CYP2C9LMNA
SCHEMBL11703609 0.85 SMN1; SMN2 (0.46) PTGS1HPGDALDH1A1CYP2C9LMNA
SCHEMBL11702059 0.84 HPGD (0.50) PTGS1HPGDALDH1A1CYP2C9LMNA
SCHEMBL11707683 0.81 HPGD (0.42) PTGS1HPGDALDH1A1CYP2C9LMNA
SCHEMBL11707677 0.81 HPGD (0.42) PTGS1HPGDALDH1A1CYP2C9LMNA
SCHEMBL11727367 0.81 GAA (0.44) PTGS1HPGDALDH1A1CYP2C9LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118382415-A Ultrasonic enhanced nano preparation continuous and large-scale production method 上海弼领生物技术有限公司 2024-07-23 CN claimed
CN-118141602-A Lacrimal canaliculus embolism 上海曙瑞科技有限公司 2024-06-07 CN claimed
CN-120129676-A Compounds, compositions, and methods thereof 海湃泰克(北京)生物医药科技有限公司 2025-06-10 CN disclosed
CN-119698283-A Use of JAK inhibitors in the management of inflammation-related depression and Central Nervous System (CNS) pathologies 爱默蕾大学 2025-03-25 CN disclosed
CN-119654179-A Balloon catheter with reduced residual stenosis and method of use 开金血管公司 2025-03-18 CN disclosed
CN-112739406-B Medical balloon catheter with enhanced pushability 开金血管公司 2024-12-24 CN disclosed
CN-119013042-A Companion diagnosis of human CEACAM1 targeted therapeutics 布里格姆及妇女医院股份有限公司 2024-11-22 CN disclosed
CN-118891043-A Compositions comprising lipid compounds and methods of making and using the same 俄亥俄州创新基金会 2024-11-01 CN disclosed
CN-118591372-A Diamino lipid (DAL) compounds and pharmaceutical compositions comprising immunotherapeutic agents 俄亥俄州创新基金会 2024-09-03 CN disclosed
CN-118338914-A Compositions comprising amino lipid compounds and methods of making and using the same 俄亥俄州创新基金会 2024-07-12 CN disclosed
CN-118141602-A Lacrimal canaliculus embolism 上海曙瑞科技有限公司 2024-06-07 CN disclosed
CN-110678543-B In vitro culture system and method of use thereof 耶达研究及发展有限公司 2024-04-09 CN disclosed
CN-117426772-A Dual function acrylate hydrogel film for diffusion limiting films and attenuating foreign body reactions 美敦力迷你迈德公司 2024-01-23 CN disclosed
CN-117280030-A Agents, compositions and methods for treating hypoxia and ischemia related conditions 梅兰德制药公司 2023-12-22 CN disclosed
CN-110325202-B Virus-like particles of hepatitis B virus pre-S protein 佐治亚州立大学研究基金会公司 2023-10-31 CN disclosed
CN-115038488-A Methods and devices for delivering cell therapies 斯特姆普莱特公司 2022-09-09 CN disclosed