Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAT2 | Q10469 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | PLAU | P00749 | 4/20 | 0.30 |
| ▸ | PLG | P00747 | 3/20 | 0.30 |
| ▸ | PLAT | P00750 | 3/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1332390 | 1.00 | MGAT2 (0.33) | MGAT2DGAT1SIRT2MEN1RAB9A | |
| SCHEMBL12573695 | 1.00 | MGAT2 (0.33) | MGAT2DGAT1SIRT2MEN1RAB9A | |
| SCHEMBL1333836 | 1.00 | MGAT2 (0.33) | MGAT2DGAT1SIRT2MEN1RAB9A | |
| SCHEMBL29910222 | 1.00 | MGAT2 (0.33) | MGAT2DGAT1SIRT2MEN1RAB9A | |
| SCHEMBL12573700 | 0.94 | MAPT (0.35) | SIRT2MEN1RAB9AKMT2A | |
| SCHEMBL1333729 | 0.94 | CTSL (0.34) | SIRT2MEN1RAB9AKMT2AMAPK14 | |
| SCHEMBL1333587 | 0.94 | MAPT (0.35) | SIRT2MEN1RAB9AKMT2A | |
| SCHEMBL30914179 | 0.93 | MGAT2 (0.32) | MGAT2DGAT1SIRT2MEN1RAB9A | |
| SCHEMBL1332469 | 0.93 | MGAT2 (0.32) | MGAT2DGAT1SIRT2MEN1RAB9A | |
| SCHEMBL1333043 | 0.91 | CTSL (0.34) | SIRT2MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718754-B1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL INC (US) | 2024-01-24 | — | — | EP | disclosed |
| EP-2895896-B1 | A PHOTOCHROMIC ARTICLE HAVING AT LEAST PARTIALLY CROSSED POLARIZED PHOTOCHROMIC-DICHROIC AND FIXED-POLARIZED LAYERS | TRANSITIONS OPTICAL INC (US) | 2022-11-02 | — | — | EP | disclosed |