Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12573751 | 1.00 | RAB9A (0.31) | RAB9ASMN1; SMN2MCHR1NPC1TP53 | |
| SCHEMBL1332863 | 1.00 | RAB9A (0.31) | RAB9ASMN1; SMN2MCHR1NPC1TP53 | |
| SCHEMBL29910196 | 0.93 | HTR2A (0.32) | SMN1; SMN2ALOX15MAPK1MAPTMEN1 | |
| SCHEMBL12573734 | 0.93 | HTR2A (0.32) | SMN1; SMN2ALOX15MAPK1MAPTMEN1 | |
| SCHEMBL1334125 | 0.93 | HTR2A (0.32) | SMN1; SMN2ALOX15MAPK1MAPTMEN1 | |
| SCHEMBL12573705 | 0.92 | RAB9A (0.35) | RAB9ASMN1; SMN2MCHR1NPC1TP53 | |
| SCHEMBL1333738 | 0.92 | RAB9A (0.35) | RAB9ASMN1; SMN2MCHR1NPC1TP53 | |
| SCHEMBL29910323 | 0.92 | RAB9A (0.35) | RAB9ASMN1; SMN2MCHR1NPC1TP53 | |
| SCHEMBL1332401 | 0.91 | — | — | |
| SCHEMBL29910192 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718755-B1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL INC (US) | 2024-05-29 | — | — | EP | disclosed |
| EP-2895896-B1 | A PHOTOCHROMIC ARTICLE HAVING AT LEAST PARTIALLY CROSSED POLARIZED PHOTOCHROMIC-DICHROIC AND FIXED-POLARIZED LAYERS | TRANSITIONS OPTICAL INC (US) | 2022-11-02 | — | — | EP | disclosed |