Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.34 |
| ▸ | HAVCR2 | Q8TDQ0 | 3/20 | 0.31 |
| ▸ | WEE1 | P30291 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23326638 | 1.00 | KDM4E (0.35) | KDM4ERXFP1ALDH1A1HPGDHTT | |
| SCHEMBL25456980 | 0.81 | ADORA2A (0.31) | KDM4ERXFP1ALDH1A1HPGDHTT | |
| SCHEMBL29910281 | 0.81 | TLR7 (0.36) | KDM4ERXFP1ALDH1A1HPGDHTT | |
| SCHEMBL29861520 | 0.81 | PIK3CA (0.36) | KDM4ERXFP1ALDH1A1HPGDHTT | |
| SCHEMBL23326861 | 0.81 | PIK3CA (0.36) | KDM4ERXFP1ALDH1A1HPGDHTT | |
| SCHEMBL23326542 | 0.81 | TLR7 (0.36) | KDM4ERXFP1ALDH1A1HPGDHTT | |
| SCHEMBL29861864 | 0.78 | RXFP1 (0.40) | KDM4ERXFP1ALDH1A1HPGDHTT | |
| SCHEMBL23326645 | 0.78 | RXFP1 (0.40) | KDM4ERXFP1ALDH1A1HPGDHTT | |
| SCHEMBL18640848 | 0.78 | ADORA2A (0.33) | KDM4ERXFP1ALDH1A1HPGDHTT | |
| SCHEMBL23326744 | 0.77 | HSD17B10 (0.33) | KDM4ERXFP1ALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425742-A | Bicyclic heteroaryl compounds and uses thereof | 锐新医药公司 | 2023-07-14 | — | — | CN | disclosed |
| EP-4055017-A1 | BICYCLIC HETEROARYL COMPOUNDS AND USES THEREOF | Revolution Medicines, Inc. (US) | 2022-09-14 | — | — | EP | disclosed |