Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | WEE1 | P30291 | 2/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23326542 | 1.00 | TLR7 (0.36) | TLR7KDM4EADORA2AADORA1EGFR | |
| SCHEMBL23326638 | 0.81 | KDM4E (0.35) | KDM4EEGFRALDH1A1HPGDJAK2 | |
| SCHEMBL29910267 | 0.81 | KDM4E (0.35) | KDM4EEGFRALDH1A1HPGDJAK2 | |
| SCHEMBL18640848 | 0.78 | ADORA2A (0.33) | KDM4EADORA2AADORA1ALDH1A1HPGD | |
| SCHEMBL29861884 | 0.77 | EGFR (0.35) | KDM4EADORA2AADORA1EGFRFGFR1 | |
| SCHEMBL23326642 | 0.77 | EGFR (0.35) | KDM4EADORA2AADORA1EGFRFGFR1 | |
| SCHEMBL25456980 | 0.75 | ADORA2A (0.31) | KDM4EADORA2AADORA1ALDH1A1HPGD | |
| SCHEMBL25140894 | 0.73 | PDE1A (0.45) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23326598 | 0.72 | SOS1 (0.51) | KDM4EALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL24582806 | 0.71 | SOS1 (0.48) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055017-A1 | BICYCLIC HETEROARYL COMPOUNDS AND USES THEREOF | Revolution Medicines, Inc. (US) | 2022-09-14 | — | — | EP | disclosed |