Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23326885 | 1.00 | SOS1 (0.57) | SOS1 | |
| SCHEMBL23326824 | 0.87 | SOS1 (0.58) | SOS1 | |
| SCHEMBL29861244 | 0.87 | SOS1 (0.58) | SOS1 | |
| SCHEMBL24672117 | 0.77 | JAK2 (0.43) | — | |
| SCHEMBL23345366 | 0.76 | SOS1 (0.46) | SOS1 | |
| SCHEMBL29861298 | 0.76 | SOS1 (0.46) | SOS1 | |
| SCHEMBL23326798 | 0.76 | SOS1 (0.46) | SOS1 | |
| SCHEMBL29861735 | 0.72 | SOS1 (0.85) | SOS1 | |
| SCHEMBL30556399 | 0.71 | JAK2 (0.42) | SOS1 | |
| SCHEMBL24672007 | 0.70 | SLC22A12 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055017-A1 | BICYCLIC HETEROARYL COMPOUNDS AND USES THEREOF | Revolution Medicines, Inc. (US) | 2022-09-14 | — | — | EP | disclosed |