Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 3/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | ADA | P00813 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29663112 | 0.86 | ADA (0.47) | KDM5AKDM4CKDM5BADAKDM4E | |
| SCHEMBL29663447 | 0.86 | ADA (0.47) | KDM5AKDM4CKDM5BADAKDM4E | |
| SCHEMBL18040235 | 0.86 | ADA (0.47) | KDM5AKDM4CKDM5BADAKDM4E | |
| SCHEMBL27781647 | 0.85 | KDM5A (0.46) | KDM5AKDM4CKDM5BADAKDM4E | |
| SCHEMBL29215817 | 0.85 | KDM5A (0.46) | KDM5AKDM4CKDM5BADAKDM4E | |
| SCHEMBL29215894 | 0.85 | KDM5A (0.46) | KDM5AKDM4CKDM5BADAKDM4E | |
| SCHEMBL30291411 | 0.83 | KDM5A (0.39) | KDM5AKDM4CKDM5BADAKDM4E | |
| SCHEMBL30268818 | 0.81 | KDM4E (0.40) | KDM5AKDM4CKDM5BADAKDM4E | |
| SCHEMBL710186 | 0.80 | KDM5A (0.48) | KDM5AADAKDM4E | |
| SCHEMBL29663383 | 0.80 | NOTUM (0.45) | KDM5AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220289751-A1 | COMPOUND HAVING KDM5 INHIBITORY ACTIVITY AND PHARMACEUTICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220289751-A1 | COMPOUND HAVING KDM5 INHIBITORY ACTIVITY AND PHARMACEUTICAL USE THEREOF | KDM5A, KDM1B, KDM5D | KDM5A 1/4885KDM4C 35/4885KDM5B 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.