Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | ACR | P10323 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249466 | 1.00 | LMNA (0.61) | LMNAL3MBTL1PRSS1ACR | |
| SCHEMBL31297752 | 0.87 | LMNA (0.48) | LMNAL3MBTL1PRSS1ACR | |
| SCHEMBL10600506 | 0.86 | LMNA (0.59) | LMNAL3MBTL1 | |
| SCHEMBL20735025 | 0.85 | PRSS1 (0.56) | LMNAL3MBTL1PRSS1ACR | |
| SCHEMBL29910599 | 0.85 | PRSS1 (0.56) | LMNAL3MBTL1PRSS1ACR | |
| SCHEMBL27881694 | 0.84 | KMT2A (0.64) | LMNAL3MBTL1 | |
| SCHEMBL28968626 | 0.83 | LMNA (0.56) | LMNAL3MBTL1 | |
| SCHEMBL4737472 | 0.82 | SERPINE1 (0.54) | LMNAL3MBTL1PRSS1ACR | |
| SCHEMBL2478197 | 0.82 | MAPT (0.44) | LMNAL3MBTL1 | |
| SCHEMBL18668840 | 0.82 | LMNA (0.61) | LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174457-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2023-06-08 | — | — | US | claimed |
| US-20240391864-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2024-11-28 | — | — | US | disclosed |
| EP-4382518-A2 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | Iowa State University Research Foundation, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| EP-3503733-B1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2024-03-20 | — | — | EP | disclosed |
| US-20230174457-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2023-06-08 | — | — | US | disclosed |
| US-11485701-B2 | Insect repellent compounds and compositions, and methods thereof | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2022-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11485701-B2 | Insect repellent compounds and compositions, and methods thereof | C5, CYP51A1, DDT | LMNA 2644/4885L3MBTL1 164/4885PRSS1 2094/4885 |
| US-20230174457-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | C5, CYP51A1, DDT | LMNA 2644/4885L3MBTL1 164/4885PRSS1 2094/4885 |
| US-20240391864-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | C5, CYP51A1, DDT | LMNA 2644/4885L3MBTL1 164/4885PRSS1 2094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.