Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | GPR4 | P46093 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23303209 | 1.00 | EPHX2 (0.56) | EPHX2DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL30696783 | 0.87 | EPHX2 (0.56) | EPHX2DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL30812113 | 0.85 | EPHX2 (0.60) | EPHX2DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL31245991 | 0.84 | EPHX2 (0.59) | EPHX2DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL32667637 | 0.84 | EPHX2 (0.55) | EPHX2DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL32667894 | 0.84 | EPHX2 (0.55) | EPHX2DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL30696599 | 0.84 | EPHX2 (0.53) | EPHX2DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL13724597 | 0.84 | EPHX2 (0.58) | EPHX2DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL23304183 | 0.84 | EPHX2 (0.58) | EPHX2DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL31217703 | 0.84 | EPHX2 (0.58) | EPHX2DRD2DRD3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4054724-A1 | BIFUNCTIONAL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2022-09-14 | — | — | EP | disclosed |