Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | GPR4 | P46093 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 4/20 | 0.48 |
| ▸ | HRH1 | P35367 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30696664 | 0.95 | HRH2 (0.55) | EPHX2HRH2HRH1 | |
| SCHEMBL30696788 | 0.94 | EPHX2 (0.55) | EPHX2HRH2HRH1SIGMAR1 | |
| SCHEMBL30696783 | 0.88 | EPHX2 (0.56) | EPHX2GPR4KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29910776 | 0.84 | EPHX2 (0.56) | EPHX2GPR4KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23303209 | 0.84 | EPHX2 (0.56) | EPHX2GPR4KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30696817 | 0.83 | EPHX2 (0.56) | EPHX2HRH2HRH1KDM4EALDH1A1 | |
| SCHEMBL30812113 | 0.82 | EPHX2 (0.60) | EPHX2GPR4KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30696767 | 0.82 | EPHX2 (0.58) | EPHX2HRH2HRH1KDM4ESIGMAR1 | |
| SCHEMBL7402027 | 0.81 | ALDH1A1 (0.62) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31245991 | 0.81 | EPHX2 (0.59) | EPHX2GPR4KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543439-A2 | NRF2 PROTEIN DEGRADERS | Ganymede Oncology, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024006742-A2 | NRF2 PROTEIN DEGRADERS | DRACEN PHARMACEUTICALS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |