Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.47 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 6/20 | 0.44 |
| ▸ | CA1 | P00915 | 6/20 | 0.44 |
| ▸ | CA2 | P00918 | 6/20 | 0.44 |
| ▸ | CA9 | Q16790 | 6/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22917474 | 1.00 | STK17B (0.47) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL22917487 | 0.85 | STK17B (0.49) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL22917677 | 0.76 | CA12 (0.51) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL29616366 | 0.76 | CA12 (0.51) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL24742223 | 0.74 | CA12 (0.47) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL31436039 | 0.74 | STK17B (0.57) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL38661180 | 0.73 | CA12 (0.45) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL24742540 | 0.73 | LTB4R (0.51) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL24741948 | 0.72 | STK17B (0.47) | STK17BSTK17ACA12CA1CA2 | |
| SCHEMBL23857385 | 0.72 | STK17B (0.39) | STK17BSTK17ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220288069-A1 | INHIBITORS OF TYROSINE KINASE | BRIDGENE BIOSCIENCES, INC. | 2022-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220288069-A1 | INHIBITORS OF TYROSINE KINASE | ABL1, SRC, LCK | STK17B 290/4885STK17A 332/4885CA12 3877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.