Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 12/20 | 0.81 |
| ▸ | RORC | P51449 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20956439 | 1.00 | DHODH (0.81) | DHODHRORCPKMMAPTPOLB | |
| SCHEMBL19631412 | 1.00 | DHODH (0.81) | DHODHRORCPKMMAPTPOLB | |
| SCHEMBL20956565 | 0.90 | DHODH (1.00) | DHODHMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL19631365 | 0.90 | DHODH (1.00) | DHODHMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL29911563 | 0.90 | DHODH (1.00) | DHODHMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL25614473 | 0.89 | DHODH (0.69) | DHODHRORCPKMMAPTPOLB | |
| SCHEMBL20956442 | 0.82 | DHODH (1.00) | DHODHMAPTKDM4EALDH1A1GAA | |
| SCHEMBL29911504 | 0.82 | DHODH (1.00) | DHODHMAPTKDM4EALDH1A1GAA | |
| SCHEMBL19631441 | 0.82 | DHODH (1.00) | DHODHMAPTKDM4EALDH1A1GAA | |
| SCHEMBL19631360 | 0.80 | DHODH (0.78) | DHODHMAPTPOLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107375279-B | Use of novel thiazole derivatives for the treatment of inflammatory bowel disease | 华东理工大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-107459496-B | Use of thiazole derivatives for treating viral infections | 华东理工大学 | 2022-07-19 | — | — | CN | disclosed |