Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 8/20 | 1.00 |
| ▸ | GAA | P10253 | 5/20 | 0.64 |
| ▸ | MGAM | O43451 | 1/20 | 0.64 |
| ▸ | SI | P14410 | 1/20 | 0.64 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.59 |
| ▸ | RELA | Q04206 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19631441 | 1.00 | DHODH (1.00) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL20956442 | 1.00 | DHODH (1.00) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL20956482 | 0.98 | DHODH (0.95) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL19631414 | 0.98 | DHODH (0.95) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL20956437 | 0.92 | DHODH (0.85) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL19631410 | 0.92 | DHODH (0.85) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL20956524 | 0.89 | DHODH (0.80) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL19631420 | 0.89 | DHODH (0.80) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL29911542 | 0.89 | DHODH (0.80) | DHODHGAAMGAMSIMGAM2 | |
| SCHEMBL19631409 | 0.88 | DHODH (0.78) | DHODHGAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107375279-B | Use of novel thiazole derivatives for the treatment of inflammatory bowel disease | 华东理工大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-107459496-B | Use of thiazole derivatives for treating viral infections | 华东理工大学 | 2022-07-19 | — | — | CN | disclosed |