Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 19/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30261441 | 0.97 | IRAK4 (0.50) | IRAK4KCNH2CNR2 | |
| SCHEMBL20086065 | 0.97 | IRAK4 (0.50) | IRAK4KCNH2CNR2 | |
| Formic Acid SCHEMBL28976193 | 0.91 | IRAK4 (0.47) | IRAK4KCNH2 | |
| Formic Acid SCHEMBL30062335 | 0.89 | IRAK4 (0.40) | IRAK4 | |
| SCHEMBL30261532 | 0.89 | IRAK4 (0.49) | IRAK4KCNH2CNR2 | |
| SCHEMBL20086024 | 0.89 | IRAK4 (0.49) | IRAK4KCNH2CNR2 | |
| Formic Acid SCHEMBL29911777 | 0.88 | IRAK4 (0.45) | IRAK4KCNH2 | |
| SCHEMBL30051809 | 0.88 | IRAK4 (0.50) | IRAK4KCNH2 | |
| SCHEMBL20086023 | 0.88 | IRAK4 (0.50) | IRAK4KCNH2 | |
| Formic Acid SCHEMBL29911549 | 0.86 | IRAK4 (0.50) | IRAK4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115531387-A | Pyrazole amide compounds useful as IRAK inhibitors | 里格尔药品股份有限公司 | 2022-12-30 | — | — | CN | claimed |
| CN-110234637-B | Pyrazole amide compounds useful as IRAK inhibitors | 里格尔药品股份有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-110234637-B | Pyrazole amide compounds useful as IRAK inhibitors | 里格尔药品股份有限公司 | 2022-11-01 | — | — | CN | disclosed |