Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30062375 | 0.96 | MAPT (0.42) | IRAK4MAPTGAAKMT2ALMNA | |
| Formic Acid SCHEMBL28976193 | 0.92 | IRAK4 (0.47) | IRAK4GRM4 | |
| Formic Acid SCHEMBL29911539 | 0.89 | IRAK4 (0.48) | IRAK4 | |
| Formic Acid SCHEMBL29911885 | 0.89 | CTSA (0.41) | IRAK4KMT2AGRM4JAK2JAK1 | |
| Formic Acid SCHEMBL29911695 | 0.89 | IRAK4 (0.39) | IRAK4KMT2ALMNAJAK2JAK1 | |
| SCHEMBL20086023 | 0.88 | IRAK4 (0.50) | IRAK4GRM4 | |
| SCHEMBL30051809 | 0.88 | IRAK4 (0.50) | IRAK4GRM4 | |
| Formic Acid SCHEMBL28976128 | 0.87 | IRAK4 (0.37) | IRAK4GRM4JAK2JAK1GRM5 | |
| Formic Acid SCHEMBL25301575 | 0.86 | IRAK4 (0.46) | IRAK4JAK2JAK1GRM5 | |
| Formic Acid SCHEMBL29911549 | 0.86 | IRAK4 (0.50) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530194-B2 | Amide compounds and method for making and using | RIGEL PHARMACEUTICALS, INC. (US) | 2022-12-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11530194-B2 | Amide compounds and method for making and using | IRAK1, IRAK2, IRAK3 | IRAK4 4/4885MAPT 2634/4885GAA 1315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.