Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 11/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17882231 | 1.00 | RIPK1 (1.00) | RIPK1CYP3A4CYP2C9CYP2C19RAB9A | |
| SCHEMBL17882216 | 0.84 | RIPK1 (0.73) | RIPK1RAB9AALDH1A1HPGDKMT2A | |
| SCHEMBL29912765 | 0.84 | RIPK1 (0.73) | RIPK1RAB9AALDH1A1HPGDKMT2A | |
| SCHEMBL17882287 | 0.79 | RIPK1 (1.00) | RIPK1ALDH1A1HPGDDPP4DPP8 | |
| SCHEMBL29912730 | 0.79 | RIPK1 (0.65) | RIPK1RAB9AALDH1A1HPGDMEN1 | |
| SCHEMBL17882223 | 0.79 | RIPK1 (0.65) | RIPK1RAB9AALDH1A1HPGDMEN1 | |
| SCHEMBL17874104 | 0.75 | RIPK1 (0.60) | RIPK1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL29912621 | 0.75 | RIPK1 (0.60) | RIPK1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL29046387 | 0.74 | RIPK1 (0.66) | RIPK1DPP4DPP9MEN1KMT2A | |
| SCHEMBL29912817 | 0.73 | RIPK1 (0.61) | RIPK1DPP4FAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197098-B | Cell necrosis inhibitor | 北京生命科学研究所 | 2023-08-08 | — | — | CN | disclosed |
| CN-115197098-A | Cell necrosis inhibitor | 北京生命科学研究所 | 2022-10-18 | — | — | CN | disclosed |
| CN-107108467-B | Cell necrosis inhibitor | 北京生命科学研究所 | 2022-08-19 | — | — | CN | disclosed |