SCHEMBL29912890

SCHEMBL29912890

C/C=C(/C)C(=O)O[C@H]1c2c(ccc3ccc(=O)oc23)OC(C)(C)[C@H]1OC(=O)/C(C)=C\C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 15/20 1.00
▸ ALDH1A1 P00352 13/20 1.00
▸ HTT P42858 3/20 1.00
▸ MEN1 O00255 3/20 1.00
▸ KMT2A Q03164 3/20 1.00
▸ LMNA P02545 3/20 1.00
▸ MAPT P10636 3/20 1.00
▸ NPSR1 Q6W5P4 2/20 1.00
▸ SMN1; SMN2 Q16637 1/20 1.00
▸ RECQL P46063 1/20 1.00
▸ ABCB1 P08183 1/20 1.00
▸ HPGD P15428 12/20 0.94
▸ CYP3A4 P08684 3/20 0.94
▸ HSD17B10 Q99714 3/20 0.94
▸ TP53 P04637 2/20 0.94
▸ POLB P06746 2/20 0.94
▸ GAA P10253 2/20 0.94
▸ RCE1 Q9Y256 1/20 0.80
▸ TSHR P16473 2/20 0.66
▸ MAPK1 P28482 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29377909 1.00 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A
SCHEMBL13363920 1.00 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A
SCHEMBL3380751 1.00 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A
SCHEMBL31682979 1.00 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A
Pteryxin SCHEMBL31598386 0.97 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A
Pteryxin SCHEMBL14511558 0.97 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A
Pteryxin SCHEMBL14523890 0.97 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A
SCHEMBL4759420 0.97 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A
Pteryxin SCHEMBL31614319 0.97 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A
SCHEMBL30517506 0.97 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 — — EP claimed
WO-2024258363-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES SAHIN FIKRET (TR) 2024-12-19 — — WO claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 — — EP disclosed
WO-2024258363-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES SAHIN FIKRET (TR) 2024-12-19 — — WO disclosed
CN-115919992-A Traditional Chinese medicine composition for treating chronic obstructive pulmonary disease and preparation method thereof 张景祖 2023-04-07 — — CN disclosed
CN-112051353-B Gradient full-information thin-layer identification method for radix peucedani medicinal material 浙江金大康动物保健品有限公司 2022-10-11 — — CN disclosed
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