SCHEMBL3380751

SCHEMBL3380751

C/C=C(\C)C(=O)OC1c2c(ccc3ccc(=O)oc23)OC(C)(C)C1OC(=O)/C(C)=C/C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 15/20 1.00
▸ ALDH1A1 P00352 13/20 1.00
▸ HTT P42858 3/20 1.00
▸ MEN1 O00255 3/20 1.00
▸ KMT2A Q03164 3/20 1.00
▸ LMNA P02545 3/20 1.00
▸ MAPT P10636 3/20 1.00
▸ NPSR1 Q6W5P4 2/20 1.00
▸ SMN1; SMN2 Q16637 1/20 1.00
▸ RECQL P46063 1/20 1.00
▸ ABCB1 P08183 1/20 1.00
▸ HPGD P15428 12/20 0.94
▸ CYP3A4 P08684 3/20 0.94
▸ HSD17B10 Q99714 3/20 0.94
▸ TP53 P04637 2/20 0.94
▸ POLB P06746 2/20 0.94
▸ GAA P10253 2/20 0.94
▸ RCE1 Q9Y256 1/20 0.80
▸ TSHR P16473 2/20 0.66
▸ MAPK1 P28482 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29377909 1.00 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A
SCHEMBL13363920 1.00 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A
SCHEMBL31682979 1.00 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A
SCHEMBL29912890 1.00 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A
Pteryxin SCHEMBL31598386 0.97 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A
Pteryxin SCHEMBL14511558 0.97 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A
Pteryxin SCHEMBL14523890 0.97 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A
SCHEMBL4759420 0.97 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A
Pteryxin SCHEMBL31614319 0.97 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A
SCHEMBL30517506 0.97 KDM4E (1.00) KDM4EALDH1A1HTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12605323-B2 Composition for inhibiting hair graying, and use thereof LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2026-04-21 — — US claimed
US-20230330120-A1 COMPOSITION FOR PREVENTING HAIR LOSS OR PROMOTING HAIR REGROWTH LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2023-10-19 — — US claimed
US-20230201097-A1 COMPOSITION FOR INHIBITING HAIR GRAYING, AND USE THEREOF LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2023-06-29 — — US claimed
CN-115916146-A Composition for inhibiting white hair and use thereof 株式会社LG生活健康 2023-04-04 — — CN claimed
CN-114703070-A Extraction method and application of isaria endophytic fungi and secondary metabolite thereof 皖西学院 2022-07-05 — — CN claimed
US-12605323-B2 Composition for inhibiting hair graying, and use thereof LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2026-04-21 — — US disclosed
CN-119470709-A Method for simultaneously measuring effective components of peucedanin, peucedanin and hesperidin in phlegm-removing cough-relieving pill 榆林市药品检验所 2025-02-18 — — CN disclosed
CN-119241555-A A method for preparing praeruptorin from praeruptorin A 浙江工业大学 2025-01-03 — — CN disclosed
CN-118749430-A Method for promoting growth of pre Hu Zupei seedlings and secondary metabolites 皖西学院 2024-10-11 — — CN disclosed
CN-116531471-B Traditional Chinese medicine mixture for treating syndrome of damp-heat attacking lung caused by virus infection 河南中医药大学第一附属医院 2024-05-14 — — CN disclosed
US-20230330120-A1 COMPOSITION FOR PREVENTING HAIR LOSS OR PROMOTING HAIR REGROWTH LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2023-10-19 — — US disclosed
US-20230330120-A1 COMPOSITION FOR PREVENTING HAIR LOSS OR PROMOTING HAIR REGROWTH LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2023-10-19 — — US disclosed
CN-115804768-A Application of peucedanum praeruptorum dunn in preparing medicine for treating nerve degenerative disease 北京大学 2023-03-17 — — CN disclosed
CN-112051353-B Gradient full-information thin-layer identification method for radix peucedani medicinal material 浙江金大康动物保健品有限公司 2022-10-11 — — CN disclosed
CN-114916388-A Corn intercropping planting method for reducing early bolting rate of peucedanum praeruptorum dunn 华容县保丰中药材种植专业合作社 2022-08-19 — — CN disclosed
CN-114703070-A Extraction method and application of isaria endophytic fungi and secondary metabolite thereof 皖西学院 2022-07-05 — — CN disclosed
CN-114558000-A Application of peucedanum praeruptorum dunn in preparation of medicine for treating melanoma 北京济全生物科技有限公司 2022-05-31 — — CN disclosed
CN-114324482-A Real-time monitoring method for excessive application of chemical fertilizer in medicinal material cultivation process 浙江省中药研究所有限公司 2022-04-12 — — CN disclosed
WO-2022045385-A1 COMPOSITION FOR PREVENTING HAIR LOSS OR PROMOTING HAIR REGROWTH 주식회사 엘지생활건강 2022-03-03 — — WO disclosed
WO-2010053340-A2 SKIN-WHITENING COMPOSITION 주식회사 알엔에스 (KR) 2010-05-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605323-B2 Composition for inhibiting hair graying, and use thereof CTNND1, CTNNB1, GSK3B KDM4E 4651/4885ALDH1A1 3922/4885HTT 1604/4885
US-20230330120-A1 COMPOSITION FOR PREVENTING HAIR LOSS OR PROMOTING HAIR REGROWTH WNT1, WNT3A, WNT3 KDM4E 3014/4885ALDH1A1 1463/4885HTT 2481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback