Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.47 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | RBP4 | P02753 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5269296 | 1.00 | GPR119 (0.52) | GPR119HRH3POLBSSTR1SSTR4 | |
| SCHEMBL2774820 | 0.86 | GPR119 (0.54) | GPR119POLB | |
| SCHEMBL21752528 | 0.85 | GPR119 (0.55) | GPR119POLB | |
| SCHEMBL5267821 | 0.85 | SCD (0.48) | HRH3SSTR1SSTR4RBP4 | |
| SCHEMBL29913160 | 0.85 | SSTR4 (0.52) | GPR119POLBSSTR1SSTR4 | |
| SCHEMBL27158022 | 0.85 | SSTR4 (0.52) | GPR119POLBSSTR1SSTR4 | |
| SCHEMBL21752524 | 0.84 | SSTR4 (0.49) | GPR119HRH3SSTR1SSTR4 | |
| SCHEMBL21752523 | 0.84 | SSTR4 (0.49) | GPR119HRH3SSTR1SSTR4 | |
| SCHEMBL5267601 | 0.84 | POLB (0.55) | GPR119POLB | |
| SCHEMBL14335009 | 0.84 | GPR119 (0.54) | GPR119POLBKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4329881-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-03-06 | — | — | EP | disclosed |
| WO-2022232383-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2022-11-03 | — | — | WO | disclosed |